A three-man, nine-woman Loudon County jury found Kristin Myers, 37, guilty of the charge for fatally shooting her 44-year-old husband, Larry Myers, on Dec. 22, 2009.
According to District Attorney General Russell Johnson, Myers' attorney, Lindsey Lander, claimed her client shot her husband in self-defense.
Jurors deliberated for 40 minutes before handing down their verdict to the contrary, according to Johnson.
The case was prosecuted by Assistant District Attorney General Frank Harvey.
According to Loudon County authorities, the couple were having difficulties. On the evening of his death, Larry Myers was in the process of moving out of his house on Huffland Drive in the city of Loudon.
Trial testimony showed his wife shot him in the back as he loaded the trunk of his car with his clothes and other belongings, according to Johnson.
His body was discovered by a passerby the next morning in the front yard of the home, Johnson said.
Authorities began searching for Kristin Myers immediately and found her a few hours later at the EconoLodge in Lenoir City, according to Johnson.
Following the verdict, Criminal Court Judge E. Eugene Eblen sentenced Myers to life in prison with the possibility of parole. She will have to serve at least 51 years behind bars.